It is a breakthrough in the fight against the Coronavirus: Australian scientists have now found a drug that the genome of Sars can kill CoV-2 within two days. This is a medium originally used against head lice, scabies, and the flow of disease: Ivermectin. Exciting, but just no time?
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“We have found that even a single dose can remove the entire viral RNA, within 48 hours,” said study leader Kylie Wagstaff. The Physician working at the Discovery Institute, the Australian Monsah University in Melbourne, Australia. “After 24 hours we noticed a significant reduction of the genome,” she said further.
In the fight against Corona: active ingredient would be available around the world
so Far, the effect of Ivermectin on Sars has been studied-CoV-2 RNA only in the laboratory. “We now need to find out, whether the dosage, we can apply it in humans, is effective – this is the next step,” said the study’s leader, more.
Ivermectin is zuglassen of the U.S. food and drug administration, FDA, is going to be very often used and considered as a safe drug, in addition to the active ingredient in the world, and voluminous available.
The researchers now want to conduct preclinical Tests and clinical trials. To determine the effect in humans, it’ll take at least a month, in addition, financial resources were urgently needed. FOCUS-Online-action #corona care: Germany helps!
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Still, it might be applied earlier than with a purpose against the Virus and developed a vaccine. Wagstaff said: “In these times, where we have a global pandemic and there is no approved treatment could help with a connection that is already available around the world, the people in the past.”
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drug acts against HI-, Dengue-, Influenza -, and Zika viruses
the scientists of The Monsah University conducted their study in conjunction with the Peter Doherty Institute of Infection and Immunity the University of Melbourne. As soon as it became known, that the pandemic began to spread, they began with the investigations of Sars-CoV-2 cells.
One of the leading medical scientists of the Doherty Institute, Leon Caly, said: “As a virologist, the part of the team was isolated in January 2020 as the first Sars-Cov-2 outside of China, and shared, I am happy about the prospect of Ivermectin as a potential drug against Covid-19 to use.” < / h3> Reported corona virus cases in Germany (click on your state)
Ivermectin is “damping” effect of the Virus
Wagstaff had already achieved in the year of 2012 a breakthrough in the case of Ivermectin and its anti-viral activity are identified. He was able to show that the parasiticide showed in laboratory tests against viruses such as HIV, Dengue, Influenza, and Zika effect.
the drug works exactly How the Coronavirus is not known. Due to its effect on other viruses, the researchers, however, have a guess: Probably “dampen” Ivermectin is the ability of the Virus to prevent the host cells to eliminate it. A Virus host cells needs to be in you dock and to benefit from them. Host cells defend themselves normally against such attacks, against Sars-CoV-2, the host cells of people who are not yet immune to the Virus but have no Chance. Corona-office hours: here you can Set your question to Covid-19
The number of Corona-ill people increases, the of the questions as well. FOCUS Online has therefore built up a network of experts and answer your questions.
Other hopefuls: chloroquine, Remdesivir, Lopinavir and Ritonavir
so Far, there are three other drugs, of which scientists achievements in the fight against the Virus promise.
This is a chloroquine which was originally developed as a Malaria prophylaxis. As a drug “retinal toxicity ” of the pharmaceutical company Bayer known, it is already for more than 80 years on the market. Bayer CEO Werner Baumann stated that there is evidence to suggest that retinal toxicity in the laboratory and in clinical studies, the viral load sink.
However, in the first Try and very high dosages are necessary, the risk of potentially serious side effects and thus large. The group intends to clarify in the studies, whether the means the people use.
another hope: Remdesivir. The Ebola drug is not yet approved. First laboratory tests showed, however, that it could act against the Virus, now the first treatment to be carried out tests on patients.
the combination of Lopinavir and Ritonavir scientists expect activity against Sars-CoV-2: The agents are for the treatment of HIV infections already approved. As a drug “Kaletra” the combination in France, was already used, there Doctors warned of serious side effects.
If you are due to the experimental methods for the treatment of Covid-19, is still under investigation. The doctors warned, however, strongly against using such drugs on their own.
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