the Federal medical-biological Agency (FMBA) of Russia, led by former Minister of health Veronika Sortovoi, developed the treatment of coronavirus infection on the basis of the antimalarial drug mefloquine
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the Federal medical-biological Agency (FMBA) of Russia, led by former Minister of health Veronika Sortovoi, developed the treatment of coronavirus infection on the basis of the antimalarial drug mefloquine. Development was conducted with the Chinese and French experience and recommendations of the world health organization (who).
“the Drug with high selectivity inhibits the cytopathic effect of the coronavirus in cell culture and inhibit its replication and the immunosuppressive effect of mefloquine inhibits activation of inflammatory response caused by the virus,” – said on the website of the FMBA.
From the release that in a treatment regimen also includes macrolide antibiotics and synthetic penicillins, adding which “not only prevents the formation of secondary bacterial and viral syndrome, but also can increase the concentration of antiviral agents in the blood plasma and the lungs.” The Agency believes that this way can effectively treat coronavirus patients with various degrees of severity.
the scheme proposed to include in the training manual of the Ministry of health for the prevention, diagnosis and treatment COVID-19. FMBA also working on the creation on the basis of mefloquine are effective and safe scheme for the prevention of coronavirus, “which will allow not only to overcome the peak incidence, but also to effectively control it in the future,” said Skvortsova.
Mefloquine was developed in the USA in the 1970-ies. It is widely used for the prevention and treatment of malaria and is included in the list of essential medicines of the who. While it has serious side effects, including visual disturbances, convulsions, confusion, hallucinations, depression, panic attack, aggression, acute psychosis, hair loss, tachycardia.
the who Previously ran the program “Solidarnost” (Solidarity) to communicate with different types of treatment COVID-19 in the world. It provides for the testing of various drugs against the virus and to identify the most effective ones. The program involves 45 States
In the number of drugs that will be tested in the framework of the who got antimalarial drugs chloroquine and hydroxychloroquine, to the test which has high hopes the US President Donald trump. Studies using hydroxychloroquine in combination with antibiotikami were held in China and France, but its use in the treatment of coronavirus infection has not yet been confirmed. To use any derivatives of chloroquine without prescription and medical supervision is dangerous and can lead to death.
In the world have already been several deaths when such self-treatment. In the United States, died a resident of Arizona who, on hearing the speech of trump on TV, took chloroquine phosphate used for the treatment of parasites of aquarium fish and is different from the antimalarial chloroquine. His wife managed to save. Two more people died in Nigeria from an overdose of chloroquine, Bloomberg reported.
In Moscow on the news on the possible efficacy of antimalarial drugs with the active ingredient hydroxychloroquine these drugs began to actively buy up, despite the fact that because of the proliferation of malaria in Russia and it does not happen in large numbers. Excessive demand on medication with hydroxychloroquine led to a shortage of distributors who have already converted with new orders to manufacturers, reports Vedomosti.
March 27, the Ministry of health updated recommendations for the prevention, diagnosis and treatment COVID-19. The list of possible to prescription medicines for the treatment of the virus in adults expanded from four to six items. It’s lopinavir + ritonavir, chloroquine, hydroxychloroquine, drugs interferons. In addition, clinical trials umifenovir, ramdevpir, favipiravir.