the Russian health Ministry has published a list of possible drugs for the treatment COVID-19 in adults
NatashaFedorova / DepositPhotos Ministry of health, Recalling the existing international experience in the treatment of COVID-19, indicates that it is possible to identify several drugs that in combination can be used to fight infection
the Press service of the Mayor and Government of Moscow
the Ministry of health of Russia on Friday, 27 March, updated recommendations for the prevention, diagnosis and treatment of a new type of coronavirus SARS-CoV-2, which causes atypical pneumonia COVID-19. The document is published on the Ministry’s website on Friday.
was supplemented by a section on laboratory diagnosis of the virus, updated treatment regimens depending on the severity of the disease. The recommendations and added new sections dedicated to the treatment of infection in pregnant women and those who recently gave birth to a child. Special attention is paid to safety of medical staff and patients after contact with an infected person COVID-19.
In the new version of the list of possible recommendations for the appointment of medicines for the treatment of COVID-19 in adults was expanded from four to six items. This etiotropic drugs, which in other countries have been used in the treatment of patients with SARS-related coronaviruses SARS-CoV and MERSCoV. But they should be used in combination:
lopinavir and ritonavir – in combination (used in therapy of HIV),
chloroquine and hydroxychloroquine (anti-malaria treatment),
recombinant interferon Beta 1b (IFN-β1b) (used in multiple sclerosis),
recombinant interferon alpha 2b (IFN-A2B) (used in hepatitis C).
for the treatment of COVID-19 may prescription drugs tocilizumab and carisoma, commonly used to combat rheumatoid arthritis. But the application of tocilizumab against the coronavirus was more studied in China on patients with severe respiratory distress syndrome. There in most cases, tocilizumab was achieved in most patients, normalization of body temperature, reduction of clinical symptoms and the need for oxygen after a single injection of the drug (400 mg intravenously).
“Among drugs that are under clinical trials in patients with COVID-19, can be noted as umifenovir, ramdevpir, favipiravir. According to published reports, these drugs today can also be used in the treatment of patients with COVID-19″, – the document says. In this case, however, it is noted that currently available information is insufficient to make an unambiguous conclusion about the effectiveness of the drugs.
the Antiviral drug ribavirin was excluded from the new version.
in addition, for the prevention of pulmonary edema and brain edema patients are recommended to carry out infusion therapy. And to improve the discharge of phlegm prescribe mucoactive (acetylcysteine, Ambroxol, carbocisteine).
In its recommendations, the Ministry of health advises citizens infected with the virus, heavy drinking, and when the temperature rises make paracetamol.
the Russian Ministry of health also emphasizes that the coronavirus increases deaths by abortion and childbirth, increases the number of complications – obstetric hemorrhage, intrauterine fetal death, the development of respiratory failure and postnatal purulent-septic infections.
With the progression of respiratory failure on a background of coronavirus disease, the development of alveolar edema of the lungs, as well as in refractory septic shock for health reasons in the interests of mother and fetus is shown an emergency C-section.
in addition, doctors warn that self-medicate with the coronavirus, as in other diseases, it is impossible.
Informed in the Ministry of health recommended that doctors prescribe meds to people with chronic diseases with the maximum validity period to reduce the number of visits to clinics. This is especially important to reduce the quantities of contacts, and adherence to isolation in the spread of coronavirus infection. The health Ministry also reminded that prescription drugs to citizens suffering from chronic diseases, for the quarantine period instead of the patient will be able to give to relatives, friends or volunteers.
as of Friday, March 27, in Russia the number of patients diagnosed with the coronavirus has increased to 1036 people (+ 182 new cases per day). Three people died from coronavirus infection.