Doctors around the world report a shortage of medical ventilators. But in recent years, doctors noticed that among HIV-infected coronavirus dramatically increased the number of people with kidney failure began to be felt and the acute shortage of dialysis machines and experts who can work with such patients. Experts in the field of medicine are wondering whether striking is a dangerous virus buds directly, or in patients with weak immune systems more actively manifested comorbidities associated with this organ.
Every fourth placed on the ventilator patient with a coronavirus in the UK suffering from kidney failure, reports the Daily Mail. Moreover, experts warn that a dangerous infection is able to induce in patients the acute kidney injury, which, in the absence of emergency treatment, can lead to death.
the United Kingdom government has already announced a serious interruption in supply of equipment for hemodialysis. The authorities, however, stressed that this issue will not affect the people to the coronavirus was similar treatment.
According to the Renal Association, the British nephrologists and experts on kidney disease, in 25% of coronavirus patients on a ventilator, developed severe acute renal failure. According to the nonprofit organization Kidney Care UK, the figure is even higher and reaches 28%.
Many doctors believe that the cause of complications with the kidneys in patients with Covid-19 may be excessive activation of the immune system. For example, the immune system detects a new virus and begins to fight it, but it may offend healthy cells and organs – and, in particular, such a sensitive organ as the kidney.
According to another version, the infected often there are clots in the blood vessels, which in turn may be detrimental to the kidneys, which is a network of the finest capillaries.
the President of the Renal Association Dr Graham Lipkin told Bi-bi-si that the virus can be detected in very thin structures of the kidney.
“It also affects the viscosity of the blood, – says the expert. – The blood becomes very mucous, and since the kidneys are many small blood vessels, it lingers, so the body begins to refuse.”
it is also Known that the kidneys are closely associated with the liver and bladder. Many experts fear that, if patients with the coronavirus have problems with the kidneys, it is not excluded that in the near future they may threaten a new wave of complications even with these bodies.
Other scientists suggest that the new virus purposefully affects the kidneys.
Covid-19 enters the human body via receptors ACE2 protein that covers the surface��t cells. It is known that this membrane protein is present on the cells of the lungs, which are particularly susceptible to the virus. However, the researchers found its high expression (ie synthesis at the cellular level, controlled by certain genes) in some parts of the kidney, which indicates the susceptibility of the body to infection.
a Group of scientists of the Chinese Wuhan, in which occurred the first outbreak of new epidemics, has documented the alarming high number of deaths from renal failure among patients with confirmed coronavirus.
the Team of experts conducted the autopsy of the dead from Covid-19 and found that nine of the 26 deceased patients had acute kidney injury, and seven were discovered coronavirus particles in that body, said in an article published April 9 in the medical journal Kidney International.
“It really is a very clear suspicion that at least part of the acute kidney damage that we have seen, was the result of direct viral damage of the kidney, said a nephrologist Medical school of the University of Pittsburgh Gender Palewski. Is different from what was recorded during the outbreak of SARS in 2002”.
in Addition, there are concerns that some people have signs of kidney failure appear in the early stages of the disease, says clinical Professor of medicine Yale University Alan Kliger, watching the surge of the number of patients with Covid-19, suffering from renal failure in new York.
“it Was clear that the buds have become a target of the coronavirus,” said he to the Irish publication TheJournal.ie. Klinger also added that the virus of the new type is about five times has increased the need for renal replacement therapy.
“Pandemic moves in waves and not all happening at once, the Professor said. We have to think globally, to think about the reserves that can be directed where they are needed”.