The results of a recent study suggest a link between a plant-based diet and the risk of colorectal cancer in men.

The study assessed the associations between predefined plant-based diet indices and colorectal cancer risk (CRC). In addition, it was examined whether the association varies according to gender, ethnicity and tumor anatomy.

A total of 79,952 men and 93,475 women took part in the multiethnic cohort study. The primary endpoint was the incidence of invasive colorectal cancer. Cox models were used to estimate colorectal cancer risk across quintiles of three plant-based diets:

During a mean follow-up of 19.2 years, 4976 cases of colorectal cancer were identified. In males, the multivariate-adjusted hazard ratio (HR) for the highest vs. lowest quintile was 0.77 (95% confidence interval, CI: 0.67-0.88) for plant-based diets. The risk was also reduced for a healthy plant-based diet (HR: 0.80; 95% CI: 0.70-0.91). However, no significant connection could be found for unhealthy plant-based diet in men. No significant association was found for any of the nutritional indices in women. In males, the inverse association for a plant-based diet was stronger in Japanese, American, Native American, and White groups than in African American or Hispanic groups (p for heterogeneity = 0.01). The association was stronger for left colon and rectum tumors than for right tumors (p for heterogeneity = 0.005). The reduced risk with a healthy plant-based diet was consistent across all ethnic groups.

Greater adherence to a diet high in healthy plant-based foods is associated with a reduced risk of colorectal cancer in men. This correlation could not be shown for women. The strength of the association in males varies by ethnicity and the anatomy of the tumor.

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Quelle: Kim, J., Boushey, C.J., Wilkens, L.R., Haiman, C.A., Merchant, L.,

Photo: Pexels/ Anna Shvets

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Lady.Health originally wrote about this article “What kind of diet reduces the risk of colon cancer in men”.