Vaccines, medicinal teas, antibodies: like trying to treat a new coronavirus COVID-19
NIAID / Flickr Scientists from Utrecht University in the Netherlands carried out a study on the effectiveness of human antibodies in the fight with a new coronavirus
Chunyan Wang et al.
Scientists from Utrecht University in the Netherlands carried out a study on the effectiveness of human antibodies in the fight against the novel coronavirus.
it turned Out that they don’t give the virus SARS-CoV-2 to attach to the cell and penetrate it. While the research is in peer review in the scientific journal Nature, and may be consulted on the portal preprints and BioRxiv.
As reported by RTVi, the antibodies consisting of blood plasma protein, can be called a superweapon that produces the immune system to fight viruses. Their creation involved the B-lymphocytes – a kind of factory for the production of these weapons. Antibodies bind to the viruses themselves, not allowing the latter to contact with the cells and penetrate them.
back in the 1970-ies the immunologists Georges köhler and Cesar Milistan has revolutionized the use of antibodies, for which he received the Nobel prize. Their discovery was to create a mechanism for the production of monoclonal antibodies – they bind with a specific antigen. Roughly speaking, this point a super-weapon that blocks certain pathogens.
It is such a monoclonal antibody has decided to use the experts from Utrecht and Rotterdam universities in their study. They took antibodies, frozen after SARS, and applied them against the new coronavirus. In the end, they showed the effectiveness against SARS-CoV-2.
According to the scientists, if the results are confirmed, the antibodies can help as have not contracted the coronavirus, and the already ill COVID-19. At the same time they warn against hasty conclusions: the current study is only the first step.
Recall that the current coronavirus SARS-CoV-2 has a connection with the coronavirus SARS-CoV, which in 2002-2003 was the cause of the epidemic of severe acute respiratory syndrome (SARS, a disease better known as SARS).
Both coronaviruses are similar in structure to “spikes” – it is the same at 77%. The same methods of penetration into the body. Is the similarity of the old and new coronaviruses have allowed Dutch scientists to find a possible method to combat the pandemic.
At the same time between “relatives” there is a significant difference – the first experiments, the results of which were published in February in the journal Science, showed that due to different structure of antibody to SARS-CoV do not work against the new coronavirus. Scientists have noted the overall similarity of the two viruses, but SARS-CoV-2 has a greater affinity (bond strength with purpose) than its predecessor.
Note that in parallel with the news about the alleged efficiency of antibodies to the new coronavirus in Seattle started testing an experimental vaccine nand people. According to the American national Institute of Allergy and infectious diseases (NIAID), in a test involved 45 healthy volunteers from 18 to 55 years, which will introduce two doses with an interval of 28 days. Scientists will monitor the participants during the year; experts hope to figure out how the effectiveness of the vaccine and its safety.
the vaccine Itself has also developed due to the similarity in SARS-CoV-2 and SARS-CoV, according to RTVi. In addition, the researchers drew attention to the common features of the novel coronavirus and MERS-CoV that caused the middle East respiratory syndrome (MERS) outbreak which occurred in 2013. In fact, the vaccine experience in Seattle, is a variant of the experimental vaccine for MERS, which was developed at the National Institute of Allergy and infectious diseases (NIAID). The researchers adapted it to the characteristics of the novel coronavirus.
the U.S. NIAID Director Anthony Fauci said at a record speed since the determination of the genetic sequence of the virus prior to testing on humans, it took only 66 days.
the Doctors report that in most cases COVID-19 is mild. But medical supervision is required for elderly and disabled people who have chronic diseases: diabetes, cardiovascular disease or asthma.
Specific medications from COVID-19 or vaccine that would prevent infection with coronavirus, yet. The world health organization says that people who are infected need symptomatic treatment. That is, the use of antipyretics at high temperature or painkillers for headaches.
“Some Western, traditional or home remedies can bring relief to the sick and to relieve the symptoms COVID-19. But the evidence that modern medicine can prevent or cure disease, no. The who does not recommend self-medication with any drugs, including antibiotic”, – stated on the who website.
At home coronavirus in China – along with antiviral drugs, whose efficacy has not yet been confirmed, the infected also give traditional media. One of these is a special decoction of different herbs to “cleanse the lungs and detoxification”. Deputy head of the National administration of traditional Chinese medicine Yu Yanhong reports that traditional vehicles help to increase the immunity of the entire body and help get rid of the disease. As stated on the website of China’s state Council, such funds had allegedly helped in the past – for example, when the epidemic SARS. Recall, evidence of effectiveness in the treatment of coronavirus traditional Chinese medicine no.