In our gut to do on closer inspection, a true cosmos. Of the on and in us, live about 100 trillion bacteria-about 99 percent of the are in our digestive organ at home. The sum of all the microscopic sub-tenants in the coils of our stomach are called gut flora. The biggest part, more than 400 species that live in the colon.

The bacteria in our gut are not the only pathogens that must be fought. Rather, they perceive very useful functions for the people. How useful they are, begins to understand the science, but only just. It is believed that they produce from indigestible dietary fiber, short-chain fatty acids, which cover a large part of the energy needs of the colon mucosa.

in Addition, they provide several important vitamins, such as Biotin, folic acid, or vitamins B2, B12 and Vitamin K. Extremely important our bacteria for the immune system. The intestinal mucosa has an enormous surface – one to two tennis courts in the intestine would measure. The settling in the “good” bacteria prevent pathogenic germs from spreading.

Prof. Stephan Vavricka from the centre for gastroenterology and Hepatology, explains: “most likely, the intestinal bacteria that coat the intestines with a protective film against pathogenic bacteria protects. In addition, you release antibiotic-like substances that inhibit the growth of pathogenic bacteria and activate body’s own immune system.”

antibiotics changed intestinal flora

The bacteria in the gut are, therefore, not sick-making, but even very important for us. This finely balanced System is also sensitive to disturbances. For example, by taking medications such as antibiotics. The drug is effective against sickness, bacteria, but also the good.

A 2011 study published by the Stanford University School of Medicine came to the conclusion that after three to four days of antibiotic administration, the composition of the intestinal flora changed dramatically. Around a third of the bacteria disappeared. A week after the end of treatment, the original composition was in two of the three subjects.

another study by the Swedish Institute for Infectious Disease Control found that the intestinal flora needed significantly longer than the previously thought three months to normalize again. Of particular concern: a seven-day treatment with antibiotics can cause intestinal bacteria antibiotic-resistant genes.

chemical substances from bacteria in a normal weed from the field could be the key supply for new drugs and existing antibiotic resistances to overcome.

Every fourth drug interferes with bacteria

That antibiotics attacks the “good” intestinal bacteria, of course, is suboptimal. Antibiotics, however, is normally not a permanent condition. Researchers from the “European Molecular Biology Laboratory” found that not only antibiotics attack the intestinal flora. It seems that many common drugs harm our bacteria in the digestive organ. The research team examined the effect of over 1000 commercially available products. More than a quarter, 250 of 923 of the Non-antibiotics inhibited the growth of at least one species of intestinal flora.

Kiran Patil from the research team says in a press release to the surprising results: “This is only the beginning. We don’t know yet, what kind of most of these drugs act on the microbes, as these effects occur in the human host, and how the impact on the health of the patient. We need to examine these relationships in detail, since this Knowledge could improve our understanding and the effectiveness of existing drugs is enormous.”

many

according to The researchers, the revenue could help of Non-antibiotics to antibiotic resistance. This is because General mechanisms of resistance seem to play a major role. Against both antibiotics and also other medications.

A healthy intestinal flora characterised by a high number of different bacteria. Drugs can affect this diversity. For example, by preventing the growth of certain intestinal bacteria. This leads to an incorrect composition of the intestinal flora. The consequences can be Prof. Vavricka, very different. “The effects are varied and range from diarrhea, bloating, abdominal pain to various food intolerances.” The expert advises: “drugs should be as short as necessary taken in the lowest possible dose.” (lum)